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Polymyxin B

Product Name
Polymyxin B
CAS No.
1404-26-8
Chemical Name
Polymyxin B
Synonyms
Polymyxin E see Colistin;polymyxin B 2.5sulfate entahydrate;Glucosamine Hydrochloride Impurity 32;Polymyxin B (base and/or unspecified salts)
CBNumber
CB4902083
Molecular Formula
C55H96N16O13
Formula Weight
0
MOL File
Mol file
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Polymyxin B Property

alpha 
5461 -106.3° (1N HCl)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

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Polymyxin B Chemical Properties,Usage,Production

Description

Polymyxin B was isolated by Wellcome Research Laboratories, in 1949, from the mixture of polymyxins A, B, C, and D produced byBacillus polymyxa. It was later separated into the major component, B1, and the minor component, B2. Polymyxin B is a basic polypeptide and shows strong activity against gram-negative bacteria, but its activity against gram-positive bacteria, Mycobacterium, and fungi is weak. Because of its toxicity, it is used carefully by intramuscular injection for resistant Pseudomonas aeruginosa infections, e.g., sepsis. Polymyxin B is used orally to sterilize the gut in leukemic patients, intraspinally for meningitis, or topically.

Uses

Antibacterial Aerosporin.

Definition

ChEBI: A polymyxin having a 6-methylheptanoyl group at the amino terminus.

brand name

(GlaxoSmithKline); Poly-Rx (X Gen).

Contact allergens

Active against Gram-negative bacteria, Polymyxin B is a mixture of Polymyxin B1 and B2. Sensitization occurs by topical, ophthalmic, and otic preparations. Cosensitization is frequent with other topical antibiotics like neomycin or bacitracin.

Polymyxin B Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Polymyxin B manufacturers

Shaanxi TNJONE Pharmaceutical Co., Ltd
Product
Polymyxin B2 1404-26-8
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
10000kg
Release date
2024-04-11
Firsky International Trade (Wuhan) Co., Ltd
Product
Polymyxin B 1404-26-8
Price
US $30.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20T
Release date
2023-09-26
Hebei Fengqiang Trading Co., LTD
Product
Polymyxin B 1404-26-8
Price
US $100.00/bag
Min. Order
1bag
Purity
99
Supply Ability
5000
Release date
2023-09-12